Stan J.J. Brouns

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John van der OostMicrobiology, Wageningen UniversityVerified email at wur.nl
Edze WestraProfessor of Microbiology, University of Exeter, Biosciences, ESIVerified email at exeter.ac.uk
Matthijs JoreAssistant ProfessorVerified email at radboudumc.nl
Snijders apThe Francis Crick InstituteVerified email at crick.ac.uk
Franklin L. NobregaAssociate Professor in Microbiology, University of SouthamptonVerified email at soton.ac.uk
Kira MakarovaNCBI, NIHVerified email at ncbi.nlm.nih.gov
Eugene KooninSenior Investigator, NCBI, NIHVerified email at ncbi.nlm.nih.gov
Tim KünneWageningen University and ResearchVerified email at wur.nl
Mark J DickmanProfessor of Bioanalytical Science and Engineering, Dept of Chemical and Biological EngineeringVerified email at sheffield.ac.uk
Raymond StaalsAssociate Professor, Wageningen UniversityVerified email at wur.nl
Jochem VinkVictoria University of WellingtonVerified email at vuw.ac.nz
Ana Rita CostaDepartment of Bionanoscience, Kavli Institute of Nanoscience, Delft University of TechnologyVerified email at tudelft.nl
Willem M de VosProfessor @ Microbiology Wageningen Netherlands @Helsinki FinlandVerified email at wur.nl
Konstantin SeverinovVerified email at waksman.rutgers.edu
Daan C. SwartsAssistant Professor/Personal Investigator | Wageningen University & ResearchVerified email at wur.nl
Sylvain MoineauUniversité LavalVerified email at bcm.ulaval.ca
Rodolphe BarrangouNorth Carolina State UniversityVerified email at ncsu.edu
Alexander YakuninUniversity of Toronto (Canada), Bangor University (UK)Verified email at bangor.ac.uk
FRANCISCO J.M. MOJICAUniversidad de AlicanteVerified email at gcloud.ua.es
Blake WiedenheftAssistant Professor Microbiology and Immunology, Montana State UniversityVerified email at montana.edu

Stan J.J. Brouns

Professor of Molecular Microbiology, Delft University of Technology

Verified email at tudelft.nl - Homepage

CRISPR-Cas Phage defense Bacteriophage therapy Antibiotic resistance


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Small CRISPR RNAs guide antiviral defense in prokaryotes SJJ Brouns, MM Jore, M Lundgren, ER Westra, RJH Slijkhuis, ... Science 321 (5891), 960-964, 2008	3643	2008
Evolution and classification of the CRISPR–Cas systems KS Makarova, DH Haft, R Barrangou, SJJ Brouns, E Charpentier, ... Nature Reviews Microbiology 9 (6), 467-477, 2011	3551	2011
An updated evolutionary classification of CRISPR–Cas systems KS Makarova, YI Wolf, OS Alkhnbashi, F Costa, SA Shah, SJ Saunders, ... Nature reviews microbiology 13 (11), 722-736, 2015	3073	2015
Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants KS Makarova, YI Wolf, J Iranzo, SA Shmakov, OS Alkhnbashi, SJJ Brouns, ... Nature Reviews Microbiology 18 (2), 67-83, 2020	2266	2020
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence E Semenova, MM Jore, KA Datsenko, A Semenova, ER Westra, B Wanner, ... Proceedings of the National Academy of Sciences 108 (25), 10098-10103, 2011	1057	2011
CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3 ER Westra, PBG van Erp, T Künne, SP Wong, RHJ Staals, CLC Seegers, ... Molecular cell 46 (5), 595-605, 2012	766	2012
Structural basis for CRISPR RNA-guided DNA recognition by Cascade MM Jore, M Lundgren, E Van Duijn, JB Bultema, ER Westra, ... Nature structural & molecular biology 18 (5), 529-536, 2011	742	2011
CRISPR-based adaptive and heritable immunity in prokaryotes J Van der Oost, MM Jore, ER Westra, M Lundgren, SJJ Brouns Trends in biochemical sciences 34 (8), 401-407, 2009	736	2009
Structures of the RNA-guided surveillance complex from a bacterial immune system B Wiedenheft, GC Lander, K Zhou, MM Jore, SJJ Brouns, J Van Der Oost, ... Nature 477 (7365), 486-489, 2011	610	2011
Targeting mechanisms of tailed bacteriophages FL Nobrega, M Vlot, PA De Jonge, LL Dreesens, HJE Beaumont, ... Nature Reviews Microbiology 16 (12), 760-773, 2018	517	2018
DNA-guided DNA interference by a prokaryotic Argonaute DC Swarts, MM Jore, ER Westra, Y Zhu, JH Janssen, AP Snijders, ... Nature 507 (7491), 258-261, 2014	514	2014
CRISPR interference directs strand specific spacer acquisition DC Swarts, C Mosterd, MWJ Van Passel, SJJ Brouns PloS one 7 (4), e35888, 2012	471	2012
CRISPR-Cas: adapting to change SA Jackson, RE McKenzie, RD Fagerlund, SN Kieper, PC Fineran, ... Science 356 (6333), eaal5056, 2017	457	2017
Molecular and evolutionary determinants of bacteriophage host range PA de Jonge, FL Nobrega, SJJ Brouns, BE Dutilh Trends in microbiology 27 (1), 51-63, 2019	423	2019
The CRISPRs, they are a-changin': how prokaryotes generate adaptive immunity ER Westra, DC Swarts, RHJ Staals, MM Jore, SJJ Brouns, J van der Oost Annual review of genetics 46 (1), 311-339, 2012	417	2012
CRISPRTarget: bioinformatic prediction and analysis of crRNA targets A Biswas, JN Gagnon, SJJ Brouns, PC Fineran, CM Brown RNA biology 10 (5), 817-827, 2013	373	2013
H‐NS‐mediated repression of CRISPR‐based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO ER Westra, Ü Pul, N Heidrich, MM Jore, M Lundgren, T Stratmann, ... Molecular microbiology 77 (6), 1380-1393, 2010	325	2010
Crystal structure of the CRISPR RNA–guided surveillance complex from Escherichia coli RN Jackson, SM Golden, PBG Van Erp, J Carter, ER Westra, SJJ Brouns, ... Science 345 (6203), 1473-1479, 2014	324	2014
Improving the performance of a quadrupole time-of-flight instrument for macromolecular mass spectrometry RHH van den Heuvel, E van Duijn, H Mazon, SA Synowsky, K Lorenzen, ... Analytical chemistry 78 (21), 7473-7483, 2006	316	2006
Degenerate target sites mediate rapid primed CRISPR adaptation PC Fineran, MJH Gerritzen, M Suárez-Diez, T Künne, J Boekhorst, ... Proceedings of the National Academy of Sciences 111 (16), E1629-E1638, 2014	312	2014

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