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Rafael Costa
Rafael Costa
NOVA-FCT
Dirección de correo verificada de fct.unl.pt
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Modeling formalisms in systems biology
D Machado, RS Costa, M Rocha, EC Ferreira, B Tidor, I Rocha
AMB Express 1 (1), 1-14, 2011
2482011
Galacto-oligosaccharides production during lactose hydrolysis by free Aspergillus oryzae β-galactosidase and immobilized on magnetic polysiloxane-polyvinyl alcohol
DFM Neri, VM Balcão, RS Costa, ICAP Rocha, EMFC Ferreira, ...
Food Chemistry 115 (1), 92-99, 2009
2152009
Hybrid dynamic modeling of Escherichia coli central metabolic network combining Michaelis-Menten and approximate kinetic equations
RS Costa, D Machado, I Rocha, EC Ferrreira
Biosystems 100 (2), 150-157, 2010
692010
Toward community standards and software for whole-cell modeling
D Waltemath, F Schreiber, JR Karr, CJ Myers, V Chelliah, ...
IEEE Transactions on Biomedical Engineering 63 (10), 2016
652016
Kinetic modeling of cell metabolism for microbial production
RS Costa, A Hartmann, S Vinga
Journal of biotechnology 219, 126-141, 2016
532016
Identification of switched ARX models via convex optimization and expectation maximization
A Hartmann, JM Lemos, RS Costa, J Xavier, S Vinga
Journal of Process Control 28, 9-16, 2015
502015
Exploring the gap between dynamic and constraint-based models of metabolism
D Machado, RS Costa, EC Ferreira, I Rocha, B Tidor
Metabolic engineering 14 (2), 112-119, 2012
472012
KiMoSys: a web-based repository of experimental data for KInetic MOdels of biological SYStems
RS Costa, A Veríssimo, S Vinga
BMC Systems Biology 8 (1), 85, 2014
292014
Critical perspective on the consequences of the limited availability of kinetic data in metabolic dynamic modelling
RS Costa, D Machado, I Rocha, EC Ferreira
Systems Biology, IET 5 (3), 157-163, 2011
272011
BacHBerry: BACterial Hosts for production of Bioactive phenolics from bERRY fruits
A Dudnik, AF Almeida, R Andrade, B Avila, P Bañados, D Barbay, ...
Phytochemistry reviews 17 (2), 291-326, 2018
252018
An extended dynamic model of Lactococcus lactis metabolism for mannitol and 2, 3-butanediol production
RS Costa, A Hartmann, P Gaspar, AR Neves, S Vinga
Molecular BioSystems 10 (3), 628-639, 2014
252014
A general deep hybrid model for bioreactor systems: combining First Principles with deep neural networks
J Pinto, M Mestre, J Ramos, RS Costa, G Striedner, R Oliveira
Computers & Chemical Engineering 165, 107952, 2022
232022
Root causes and outcomes of postoperative pulmonary complications after abdominal surgery: a retrospective observational cohort study
A Fernandes, J Rodrigues, P Lages, S Lança, P Mendes, L Antunes, ...
Patient Safety in Surgery 13 (1), 40, 2019
222019
Implementation of a specific rate controller in a fed-batch E. coli fermentation
I Rocha, ACA Veloso, S Carneiro, R Costa, EC Ferreira
IFAC Proceedings Volumes 41 (2), 15565-15570, 2008
212008
Identifying IIR filter coefficients using particle swarm optimization with application to reconstruction of missing cardiovascular signals
A Hartmann, JM Lemos, RS Costa, S Vinga
Engineering Applications of Artificial Intelligence 34, 193-198, 2014
162014
A critical review on modelling formalisms and simulation tools in computational biosystems
D Machado, R Costa, M Rocha, I Rocha, B Tidor, E Ferreira
Distributed Computing, Artificial Intelligence, Bioinformatics, Soft …, 2009
152009
An Overview of Mathematical Modelling in Cancer Research: Fractional Calculus as Modelling Tool
LC Vieira, RS Costa, D Valério
Fractal and Fractional 7 (8), 595, 2023
142023
The relevance of enzyme specificity for coenzymes and the presence of 6-phosphogluconate dehydrogenase for polyhydroxyalkanoates production in the metabolism of Pseudomonas sp …
J Cardinali-Rezende, A Di Genova, RA Nahat, A Steinbüchel, MF Sagot, ...
International Journal of Biological Macromolecules 163, 240-250, 2020
142020
Predictability of COVID-19 Hospitalizations, Intensive Care Unit Admissions, and Respiratory Assistance in Portugal: Longitudinal Cohort Study
A Patrício, RS Costa*, R Henriques
JMIR 23 (4), e26075, 2021
132021
Mining pre-surgical patterns able to discriminate post-surgical outcomes in the oncological domain
L Alexandre, RS Costa, LL Santos, R Henriques
IEEE Journal of Biomedical and Health Informatics, 2021
112021
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Artículos 1–20