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Roderick Beijersbergen
Roderick Beijersbergen
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Zitiert von
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Creation of human tumour cells with defined genetic elements
WC Hahn, CM Counter, AS Lundberg, RL Beijersbergen, MW Brooks, ...
Nature 400 (6743), 464-468, 1999
31021999
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
M Meyerson, CM Counter, EN Eaton, LW Ellisen, P Steiner, SD Caddle, ...
cell 90 (4), 785-795, 1997
26021997
Unresponsiveness of colon cancer to BRAF (V600E) inhibition through feedback activation of EGFR
A Prahallad, C Sun, S Huang, F Di Nicolantonio, R Salazar, D Zecchin, ...
Nature 483 (7387), 100-103, 2012
23032012
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer
K Berns, HM Horlings, BT Hennessy, M Madiredjo, EM Hijmans, K Beelen, ...
Cancer cell 12 (4), 395-402, 2007
19422007
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
K Berns, EM Hijmans, J Mullenders, TR Brummelkamp, A Velds, ...
Nature 428 (6981), 431-437, 2004
14722004
Inhibition of telomerase limits the growth of human cancer cells
WC Hahn, SA Stewart, MW Brooks, SG York, E Eaton, A Kurachi, ...
Nature medicine 5 (10), 1164-1170, 1999
14131999
Reversible and adaptive resistance to BRAF (V600E) inhibition in melanoma
C Sun, L Wang, S Huang, GJJE Heynen, A Prahallad, C Robert, ...
Nature 508 (7494), 118-122, 2014
9442014
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization
CM Counter, WC Hahn, W Wei, SD Caddle, RL Beijersbergen, ...
Proceedings of the National Academy of Sciences 95 (25), 14723-14728, 1998
8381998
Statistical methods for analysis of high-throughput RNA interference screens
A Birmingham, LM Selfors, T Forster, D Wrobel, CJ Kennedy, E Shanks, ...
Nature methods 6 (8), 569-575, 2009
6892009
Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma
T Otto, S Horn, M Brockmann, U Eilers, L Schüttrumpf, N Popov, ...
Cancer cell 15 (1), 67-78, 2009
6682009
Phosphatidylinositol 3-kinase hyperactivation results in lapatinib resistance that is reversed by the mTOR/phosphatidylinositol 3-kinase inhibitor NVP-BEZ235
PJA Eichhorn, M Gili, M Scaltriti, V Serra, M Guzman, W Nijkamp, ...
Cancer research 68 (22), 9221-9230, 2008
5902008
The ubiquitin-specific protease USP28 is required for MYC stability
N Popov, M Wanzel, M Madiredjo, D Zhang, R Beijersbergen, R Bernards, ...
Nature cell biology 9 (7), 765-774, 2007
5812007
MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling
S Huang, M Hölzel, T Knijnenburg, A Schlicker, P Roepman, U McDermott, ...
Cell 151 (5), 937-950, 2012
5082012
CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes
B Evers, K Jastrzebski, JPM Heijmans, W Grernrum, RL Beijersbergen, ...
Nature biotechnology 34 (6), 631-633, 2016
4912016
E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo.
RL Beijersbergen, RM Kerkhoven, L Zhu, L Carlée, PM Voorhoeve, ...
Genes & development 8 (22), 2680-2690, 1994
4881994
Inducing and exploiting vulnerabilities for the treatment of liver cancer
C Wang, S Vegna, H Jin, B Benedict, C Lieftink, C Ramirez, ...
Nature 574 (7777), 268-272, 2019
3792019
Neutrophils kill antibody-opsonized cancer cells by trogoptosis
HL Matlung, L Babes, XW Zhao, M van Houdt, LW Treffers, DJ van Rees, ...
Cell reports 23 (13), 3946-3959. e6, 2018
3792018
Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1
C Kuijl, NDL Savage, M Marsman, AW Tuin, L Janssen, DA Egan, ...
Nature 450 (7170), 725-730, 2007
3792007
Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes.
RL Beijersbergen, L Carlée, RM Kerkhoven, R Bernards
Genes & development 9 (11), 1340-1353, 1995
3661995
Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3
C Sun, S Hobor, A Bertotti, D Zecchin, S Huang, F Galimi, F Cottino, ...
Cell reports 7 (1), 86-93, 2014
3592014
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