Lilian Plotkin
Lilian Plotkin
professor of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine
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Zitiert von
Zitiert von
Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity
S Kousteni, T Bellido, LI Plotkin, CA O'brien, DL Bodenner, L Han, K Han, ...
Cell 104 (5), 719-730, 2001
Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin
LI Plotkin, RS Weinstein, AM Parfitt, PK Roberson, SC Manolagas, ...
The Journal of clinical investigation 104 (10), 1363-1374, 1999
Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength
CA O’brien, D Jia, LI Plotkin, T Bellido, CC Powers, SA Stewart, ...
Endocrinology 145 (4), 1835-1841, 2004
Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids
M Almeida, LI Han, M Martin-Millan, LI Plotkin, SA Stewart, PK Roberson, ...
Journal of Biological Chemistry 282 (37), 27285-27297, 2007
Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis
T Bellido, AA Ali, I Gubrij, LI Plotkin, Q Fu, CA O’brien, SC Manolagas, ...
Endocrinology 146 (11), 4577-4583, 2005
Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss
JI Aguirre, LI Plotkin, SA Stewart, RS Weinstein, AM Parfitt, SC Manolagas, ...
Journal of bone and mineral research 21 (4), 605-615, 2006
Reversal of bone loss in mice by nongenotropic signaling of sex steroids
S Kousteni, JR Chen, T Bellido, L Han, AA Ali, CA O'Brien, L Plotkin, Q Fu, ...
Science 298 (5594), 843-846, 2002
Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading
X Tu, Y Rhee, KW Condon, N Bivi, MR Allen, D Dwyer, M Stolina, ...
Bone 50 (1), 209-217, 2012
Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts: a putative explanation for why intermittent administration is …
T Bellido, AA Ali, LI Plotkin, Q Fu, I Gubrij, PK Roberson, RS Weinstein, ...
Journal of Biological Chemistry 278 (50), 50259-50272, 2003
Control of bone mass and remodeling by PTH receptor signaling in osteocytes
CA O'Brien, LI Plotkin, C Galli, JJ Goellner, AR Gortazar, MR Allen, ...
PloS one 3 (8), e2942, 2008
Transduction of cell survival signals by connexin-43 hemichannels
LI Plotkin, SC Manolagas, T Bellido
Journal of Biological Chemistry 277 (10), 8648-8657, 2002
Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids
S Kousteni, L Han, JR Chen, M Almeida, LI Plotkin, T Bellido, ...
The Journal of clinical investigation 111 (11), 1651-1664, 2003
Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs
LI Plotkin, I Mathov, JI Aguirre, AM Parfitt, SC Manolagas, T Bellido
American Journal of Physiology-Cell Physiology 289 (3), C633-C643, 2005
Novel actions of bisphosphonates in bone: preservation of osteoblast and osteocyte viability
T Bellido, LI Plotkin
Bone 49 (1), 50-55, 2011
Bisphosphonates and estrogens inhibit osteocyte apoptosis via distinct molecular mechanisms downstream of extracellular signal-regulated kinase activation
LI Plotkin, JI Aguirre, S Kousteni, SC Manolagas, T Bellido
Journal of Biological Chemistry 280 (8), 7317-7325, 2005
Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo
Y Rhee, N Bivi, E Farrow, V Lezcano, LI Plotkin, KE White, T Bellido
Bone 49 (4), 636-643, 2011
Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone
X Tu, J Delgado-Calle, KW Condon, M Maycas, H Zhang, N Carlesso, ...
Proceedings of the National Academy of Sciences 112 (5), E478-E486, 2015
Cell autonomous requirement of connexin 43 for osteocyte survival: consequences for endocortical resorption and periosteal bone formation
N Bivi, KW Condon, MR Allen, N Farlow, G Passeri, LR Brun, Y Rhee, ...
Journal of Bone and Mineral Research 27 (2), 374-389, 2012
Connexin 43 is required for the anti‐apoptotic effect of bisphosphonates on osteocytes and osteoblasts in vivo
LI Plotkin, V Lezcano, J Thostenson, RS Weinstein, SC Manolagas, ...
Journal of Bone and Mineral Research 23 (11), 1712-1721, 2008
PTH receptor signaling in osteocytes governs periosteal bone formation and intracortical remodeling
Y Rhee, MR Allen, K Condon, V Lezcano, AC Ronda, C Galli, N Olivos, ...
Journal of Bone and Mineral Research 26 (5), 1035-1046, 2011
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