Gene expression elucidates functional impact of polygenic risk for schizophrenia M Fromer, P Roussos, SK Sieberts, JS Johnson, DH Kavanagh, ... Nature neuroscience 19 (11), 1442-1453, 2016 | 1056 | 2016 |
A multi-omic atlas of the human frontal cortex for aging and Alzheimer’s disease research PL De Jager, Y Ma, C McCabe, J Xu, BN Vardarajan, D Felsky, HU Klein, ... Scientific data 5 (1), 1-13, 2018 | 354 | 2018 |
Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases M Allen, MM Carrasquillo, C Funk, BD Heavner, F Zou, CS Younkin, ... Scientific data 3 (1), 1-10, 2016 | 352 | 2016 |
Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1 Y Shu, MK Leabman, B Feng, LM Mangravite, CC Huang, D Stryke, ... Proceedings of the National Academy of Sciences 100 (10), 5902-5907, 2003 | 340 | 2003 |
The psychencode project S Akbarian, C Liu, JA Knowles, FM Vaccarino, PJ Farnham, GE Crawford, ... Nature neuroscience 18 (12), 1707-1712, 2015 | 327 | 2015 |
The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease M Wang, ND Beckmann, P Roussos, E Wang, X Zhou, Q Wang, C Ming, ... Scientific data 5 (1), 1-16, 2018 | 316 | 2018 |
Genome-wide association of lipid-lowering response to statins in combined study populations MJ Barber, LM Mangravite, CL Hyde, DI Chasman, JD Smith, CA McCarty, ... PloS one 5 (3), e9763, 2010 | 280 | 2010 |
Unsupervised analysis of transcriptomics in bacterial sepsis across multiple datasets reveals three robust clusters TE Sweeney, TD Azad, M Donato, WA Haynes, TM Perumal, R Henao, ... Critical care medicine 46 (6), 915-925, 2018 | 248 | 2018 |
Indicators of retention in remote digital health studies: a cross-study evaluation of 100,000 participants A Pratap, EC Neto, P Snyder, C Stepnowsky, N Elhadad, D Grant, ... NPJ digital medicine 3 (1), 21, 2020 | 234 | 2020 |
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy LM Mangravite, BE Engelhardt, MW Medina, JD Smith, CD Brown, ... Nature 502 (7471), 377-380, 2013 | 229 | 2013 |
Meta-analysis of the Alzheimer’s disease human brain transcriptome and functional dissection in mouse models YW Wan, R Al-Ouran, CG Mangleburg, TM Perumal, TV Lee, K Allison, ... Cell reports 32 (2), 2020 | 212 | 2020 |
Clinical implications of pharmacogenomics of statin treatment LM Mangravite, CF Thorn, RM Krauss The pharmacogenomics journal 6 (6), 360-374, 2006 | 207 | 2006 |
Integrative modeling of eQTLs and cis-regulatory elements suggests mechanisms underlying cell type specificity of eQTLs CD Brown, LM Mangravite, BE Engelhardt PLoS genetics 9 (8), e1003649, 2013 | 194 | 2013 |
A community approach to mortality prediction in sepsis via gene expression analysis TE Sweeney, TM Perumal, R Henao, M Nichols, JA Howrylak, AM Choi, ... Nature communications 9 (1), 694, 2018 | 187 | 2018 |
Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin … RM Krauss, LM Mangravite, JD Smith, MW Medina, D Wang, X Guo, ... Circulation 117 (12), 1537-1544, 2008 | 184 | 2008 |
Crowdsourcing biomedical research: leveraging communities as innovation engines J Saez-Rodriguez, JC Costello, SH Friend, MR Kellen, L Mangravite, ... Nature Reviews Genetics 17 (8), 470-486, 2016 | 167 | 2016 |
Comprehensive evaluation of the 5XFAD mouse model for preclinical testing applications: a MODEL-AD study AL Oblak, PB Lin, KP Kotredes, RS Pandey, D Garceau, HM Williams, ... Frontiers in aging neuroscience 13, 713726, 2021 | 166 | 2021 |
Landscape of conditional eQTL in dorsolateral prefrontal cortex and co-localization with schizophrenia GWAS A Dobbyn, LM Huckins, J Boocock, LG Sloofman, BS Glicksberg, ... The American Journal of Human Genetics 102 (6), 1169-1184, 2018 | 136 | 2018 |
Pharmacogenomic discovery using cell-based models M Welsh, L Mangravite, MW Medina, K Tantisira, W Zhang, RS Huang, ... Pharmacological reviews 61 (4), 413-429, 2009 | 135 | 2009 |
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer AA Margolin, E Bilal, E Huang, TC Norman, L Ottestad, BH Mecham, ... Science translational medicine 5 (181), 181re1-181re1, 2013 | 130 | 2013 |