Kevin M Weeks
Kevin M Weeks
Kenan Distinguished Professor, University of North Carolina - Chapel Hill
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Zitiert von
Zitiert von
Architecture and secondary structure of an entire HIV-1 RNA genome
JM Watts, KK Dang, RJ Gorelick, CW Leonard, JW Bess Jr, R Swanstrom, ...
Nature 460 (7256), 711-716, 2009
RNA structure analysis at single nucleotide resolution by selective 2 ‘-hydroxyl acylation and primer extension (SHAPE)
EJ Merino, KA Wilkinson, JL Coughlan, KM Weeks
Journal of the American Chemical Society 127 (12), 4223-4231, 2005
Selective 2′-hydroxyl acylation analyzed by primer extension (SHAPE): quantitative RNA structure analysis at single nucleotide resolution
KA Wilkinson, EJ Merino, KM Weeks
Nature protocols 1 (3), 1610-1616, 2006
Accurate SHAPE-directed RNA structure determination
KE Deigan, TW Li, DH Mathews, KM Weeks
Proceedings of the National Academy of Sciences 106 (1), 97-102, 2009
RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)
NA Siegfried, S Busan, GM Rice, JAE Nelson, KM Weeks
Nature methods 11 (9), 959-965, 2014
Principles for targeting RNA with drug-like small molecules
KD Warner, CE Hajdin, KM Weeks
Nature reviews Drug discovery 17 (8), 547-558, 2018
Fragments of the HIV-1 Tat protein specifically biand TAR RNA
KM Weeks, C Ampe, SC Schultz, TA Steitz, DM Crothers
Science 249 (4974), 1281-1285, 1990
High-throughput SHAPE analysis reveals structures in HIV-1 genomic RNA strongly conserved across distinct biological states
KA Wilkinson, RJ Gorelick, SM Vasa, N Guex, A Rein, DH Mathews, ...
PLoS biology 6 (4), e96, 2008
mRNA structure determines specificity of a polyQ-driven phase separation
EM Langdon, Y Qiu, A Ghanbari Niaki, GA McLaughlin, CA Weidmann, ...
Science 360 (6391), 922-927, 2018
RNA recognition by Tat-derived peptides: interaction in the major groove?
KM Weeks, DM Crothers
Cell 66 (3), 577-588, 1991
A fast-acting reagent for accurate analysis of RNA secondary and tertiary structure by SHAPE chemistry
SA Mortimer, KM Weeks
Journal of the American Chemical Society 129 (14), 4144-4145, 2007
Advances in RNA structure analysis by chemical probing
KM Weeks
Current opinion in structural biology 20 (3), 295-304, 2010
Selective 2′-hydroxyl acylation analyzed by primer extension and mutational profiling (SHAPE-MaP) for direct, versatile and accurate RNA structure analysis
MJ Smola, GM Rice, S Busan, NA Siegfried, KM Weeks
Nature protocols 10 (11), 1643-1669, 2015
Accurate SHAPE-directed RNA secondary structure modeling, including pseudoknots
CE Hajdin, S Bellaousov, W Huggins, CW Leonard, DH Mathews, ...
Proceedings of the National Academy of Sciences 110 (14), 5498-5503, 2013
SHAPE-directed RNA secondary structure prediction
JT Low, KM Weeks
Methods 52 (2), 150-158, 2010
Catalysts from synthetic genetic polymers
AI Taylor, VB Pinheiro, MJ Smola, AS Morgunov, S Peak-Chew, C Cozens, ...
Nature 518 (7539), 427-430, 2015
RNA-Puzzles: a CASP-like evaluation of RNA three-dimensional structure prediction
JA Cruz, MF Blanchet, M Boniecki, JM Bujnicki, SJ Chen, S Cao, R Das, ...
Rna 18 (4), 610-625, 2012
Major groove accessibility of RNA
KM Weeks, DM Crothers
Science 261 (5128), 1574-1577, 1993
Genomic RNA elements drive phase separation of the SARS-CoV-2 nucleocapsid
C Iserman, CA Roden, MA Boerneke, RSG Sealfon, GA McLaughlin, ...
Molecular cell 80 (6), 1078-1091. e6, 2020
ShapeFinder: a software system for high-throughput quantitative analysis of nucleic acid reactivity information resolved by capillary electrophoresis
SM Vasa, N Guex, KA Wilkinson, KM Weeks, MC Giddings
Rna 14 (10), 1979-1990, 2008
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