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New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels
C Viappiani, S Bettati, S Bruno, L Ronda, S Abbruzzetti, A Mozzarelli, ...
Proceedings of the National Academy of Sciences 101 (40), 14414-14419, 2004
1282004
Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions
A Mozzarelli, L Ronda, S Faggiano, S Bettati, S Bruno
Blood Transfusion 8 (Suppl 3), s59, 2010
992010
Identification of a small molecule that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling
A Nakagawa, FE Lui, D Wassaf, R Yefidoff-Freedman, D Casalena, ...
ACS chemical biology 9 (10), 2318-2325, 2014
632014
Iron metabolism at the interface between host and pathogen: from nutritional immunity to antibacterial development
M Marchetti, O De Bei, S Bettati, B Campanini, S Kovachka, E Gianquinto, ...
International journal of molecular sciences 21 (6), 2145, 2020
602020
Experimental basis for a new allosteric model for multisubunit proteins
C Viappiani, S Abbruzzetti, L Ronda, S Bettati, ER Henry, A Mozzarelli, ...
Proceedings of the National Academy of Sciences 111 (35), 12758-12763, 2014
582014
PEGylation promotes hemoglobin tetramer dissociation
D Caccia, L Ronda, R Frassi, M Perrella, E Del Favero, S Bruno, B Pioselli, ...
Bioconjugate chemistry 20 (7), 1356-1366, 2009
582009
Spectroscopic and functional characterization of T state hemoglobin conformations encapsulated in silica gels
U Samuni, D Dantsker, LJ Juszczak, S Bettati, L Ronda, A Mozzarelli, ...
Biochemistry 43 (43), 13674-13682, 2004
532004
Towards a novel haemoglobin-based oxygen carrier: Euro-PEG-Hb, physico-chemical properties, vasoactivity and renal filtration
I Portörő, L Kocsis, P Herman, D Caccia, M Perrella, L Ronda, S Bruno, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1784 (10), 1402-1409, 2008
502008
Experiments on hemoglobin in single crystals and silica gels distinguish among allosteric models
ER Henry, A Mozzarelli, C Viappiani, S Abbruzzetti, S Bettati, L Ronda, ...
Biophysical Journal 109 (6), 1264-1272, 2015
402015
Evidence for two geminate rebinding states following laser photolysis of R state hemoglobin encapsulated in wet silica gels
S Sottini, S Abbruzzetti, C Viappiani, S Bettati, L Ronda, A Mozzarelli
The Journal of Physical Chemistry B 109 (23), 11411-11413, 2005
402005
Oxygen binding to heme proteins in solution, encapsulated in silica gels, and in the crystalline state
L Ronda, S Bruno, S Faggiano, S Bettati, A Mozzarelli
Methods in enzymology 437, 311-328, 2008
382008
Circular dichroism spectroscopy of tertiary and quaternary conformations of human hemoglobin entrapped in wet silica gels
L Ronda, S Bruno, C Viappiani, S Abbruzzetti, A Mozzarelli, KC Lowe, ...
Protein science 15 (8), 1961-1967, 2006
372006
Geminate rebinding in R-state hemoglobin: kinetic and computational evidence for multiple hydrophobic pockets
S Sottini, S Abbruzzetti, F Spyrakis, S Bettati, L Ronda, A Mozzarelli, ...
Journal of the American Chemical Society 127 (49), 17427-17432, 2005
362005
Immobilization of proteins in silica gel: biochemical and biophysical properties
L Ronda, S Bruno, B Campanini, A Mozzarelli, S Abbruzzetti, C Viappiani, ...
Current Organic Chemistry 19 (17), 1653-1668, 2015
352015
Determination of microscopic rate constants for CO binding and migration in myoglobin encapsulated in silica gels
S Sottini, S Abbruzzetti, C Viappiani, L Ronda, A Mozzarelli
The Journal of Physical Chemistry B 109 (41), 19523-19528, 2005
352005
Engineering tyrosine electron transfer pathways decreases oxidative toxicity in hemoglobin: implications for blood substitute design
GGA Silkstone, RS Silkstone, MT Wilson, M Simons, L Bülow, K Kallberg, ...
Biochemical Journal 473 (19), 3371-3383, 2016
332016
Comparison of the oxidative reactivity of recombinant fetal and adult human hemoglobin: implications for the design of hemoglobin-based oxygen carriers
M Simons, S Gretton, GGA Silkstone, BS Rajagopal, V Allen-Baume, ...
Bioscience reports 38 (4), BSR20180370, 2018
302018
CO rebinding kinetics to myoglobin-and R-state-hemoglobin-doped silica gels in the presence of glycerol
S Sottini, C Viappiani, L Ronda, S Bettati, A Mozzarelli
The Journal of Physical Chemistry B 108 (24), 8475-8484, 2004
302004
Crystals of tryptophan indole-lyase and tyrosine phenol-lyase form stable quinonoid complexes
RS Phillips, TV Demidkina, LN Zakomirdina, S Bruno, L Ronda, ...
Journal of Biological Chemistry 277 (24), 21592-21597, 2002
302002
Interaction of human hemoglobin and semi-hemoglobins with the Staphylococcus aureus hemophore IsdB: a kinetic and mechanistic insight
E Gianquinto, I Moscetti, O De Bei, B Campanini, M Marchetti, FJ Luque, ...
Scientific Reports 9 (1), 18629, 2019
292019
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