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Kaalak Reddy
Kaalak Reddy
The RNA Institute - University at Albany, SUNY
Verified email at albany.edu - Homepage
Title
Cited by
Cited by
Year
The disease-associated r (GGGGCC) n repeat from the C9orf72 gene forms tract length-dependent uni-and multimolecular RNA G-quadruplex structures
K Reddy, B Zamiri, SYR Stanley, RB Macgregor, CE Pearson
Journal of Biological Chemistry 288 (14), 9860-9866, 2013
4022013
Ribonuclease H2 mutations induce a cGAS/STING‐dependent innate immune response
KJ Mackenzie, P Carroll, L Lettice, Ž Tarnauskaitė, K Reddy, F Dix, ...
The EMBO journal 35 (8), 831-844, 2016
2542016
TMPyP4 porphyrin distorts RNA G-quadruplex structures of the disease-associated r (GGGGCC) n repeat of the C9orf72 gene and blocks interaction of RNA-binding proteins
B Zamiri, K Reddy, RB Macgregor, CE Pearson
Journal of Biological Chemistry 289 (8), 4653-4659, 2014
2492014
Determinants of R-loop formation at convergent bidirectionally transcribed trinucleotide repeats
K Reddy, M Tam, RP Bowater, M Barber, M Tomlinson, K Nichol Edamura, ...
Nucleic acids research 39 (5), 1749-1762, 2011
1762011
Processing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability
K Reddy, MHM Schmidt, JM Geist, NP Thakkar, GB Panigrahi, YH Wang, ...
Nucleic acids research 42 (16), 10473-10487, 2014
1232014
TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism
ME Harley, O Murina, A Leitch, MR Higgs, LS Bicknell, G Yigit, ...
Nature genetics 48 (1), 36-43, 2016
1002016
Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model
CF Moss, I Dalla Rosa, LE Hunt, T Yasukawa, R Young, AWE Jones, ...
Nucleic acids research 45 (22), 12808-12815, 2017
492017
Interconverting conformations of slipped-DNA junctions formed by trinucleotide repeats affect repair outcome
MM Slean, K Reddy, B Wu, K Nichol Edamura, M Kekis, FHT Nelissen, ...
Biochemistry 52 (5), 773-785, 2013
422013
A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels
K Reddy, JR Jenquin, OL McConnell, JD Cleary, JI Richardson, BS Pinto, ...
Proceedings of the National Academy of Sciences 116 (42), 20991-21000, 2019
312019
ITPase deficiency causes a Martsolf-like syndrome with a lethal infantile dilated cardiomyopathy
MT Handley, K Reddy, J Wills, E Rosser, A Kamath, M Halachev, ...
PLoS Genetics 15 (3), e1007605, 2019
302019
Mitigating RNA toxicity in myotonic dystrophy using small molecules
K Reddy, JR Jenquin, JD Cleary, JA Berglund
International Journal of Molecular Sciences 20 (16), 4017, 2019
262019
CCG• CGG interruptions in high‐penetrance SCA8 families increase RAN translation and protein toxicity
BA Perez, HK Shorrock, M Banez‐Coronel, T Zu, LEL Romano, ...
EMBO Molecular Medicine 13 (11), e14095, 2021
222021
RAN translation: Fragile X in the running
K Reddy, CE Pearson
Neuron 78 (3), 405-408, 2013
142013
Disease-associated inosine misincorporation into RNA hinders translation
JH Schroader, LA Jones, R Meng, HK Shorrock, JI Richardson, ...
Nucleic Acids Research 50 (16), 9306-9318, 2022
132022
Inosine triphosphate pyrophosphatase: A guardian of the cellular nucleotide pool and potential mediator of RNA function
JH Schroader, MT Handley, K Reddy
Wiley Interdisciplinary Reviews: RNA 14 (5), e1790, 2023
42023
The unusual structural properties and potential biological relevance of switchback DNA
BR Madhanagopal, H Talbot, A Rodriguez, JM Louis, H Zeghal, ...
Nature Communications 15 (1), 6636, 2024
32024
CAG repeat-selective compounds reduce abundance of expanded CAG RNAs in patient cell and murine models of SCAs
HK Shorrock, A Aliyeva, JA Frias, VA DeMeo, CD Lennon, CC DeMeo, ...
bioRxiv, 2024.08. 17.608349, 2024
22024
Quercetin selectively reduces expanded repeat RNA levels in models of myotonic dystrophy
SK Mishra, SM Hicks, JA Frias, S Vangaveti, M Nakamori, JD Cleary, ...
bioRxiv, 2023
22023
Drug screen tugs at common thread for repeat disorders
K Reddy, JD Cleary, JA Berglund
Trends in Pharmacological Sciences 41 (2), 71-73, 2020
22020
Expression levels of core spliceosomal proteins modulate the MBNL-mediated spliceopathy in DM1
JM Louis, JA Frias, JH Schroader, LA Jones, EE Davey, CD Lennon, ...
Human Molecular Genetics 33 (21), 1873-1886, 2024
12024
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