Dominic G Whittaker

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Gary MiramsCentre for Mathematical Medicine & Biology, University of NottinghamDirección de correo verificada de nottingham.ac.uk
Henggui ZhangProfessor of Biological Physics, University of ManchesterDirección de correo verificada de manchester.ac.uk
Chon Lok LeiUniversity of MacauDirección de correo verificada de um.edu.mo
Jules HancoxProfessor of Cardiac Electrophysiology, University of BristolDirección de correo verificada de bristol.ac.uk
Haibo NiUniversity of California, DavisDirección de correo verificada de ucdavis.edu
Michael ClerxResearcher, University of NottinghamDirección de correo verificada de nottingham.ac.uk
Michael A ColmanUnivesity of LeedsDirección de correo verificada de leeds.ac.uk
Al BensonUniversity of LeedsDirección de correo verificada de leeds.ac.uk
Teun P. de BoerAssociate Professor, Department of Medical Physiology, University Medical Center UtrechtDirección de correo verificada de umcutrecht.nl
Graham StuartConsultant CardiologistDirección de correo verificada de nhs.net
Aziza El HarchiUniversity of BristolDirección de correo verificada de bristol.ac.uk
David GavaghanProfessor of Computational Biology, University of OxfordDirección de correo verificada de cs.ox.ac.uk
Ismail AdeniranManchester Metropolitan UniversityDirección de correo verificada de mmu.ac.uk
Alexander V PanfilovDepartment of Physics and Astronomy, Gent UniversityDirección de correo verificada de UGent.be
Richard WilkinsonProfessor of Statistics, University of NottinghamDirección de correo verificada de nottingham.ac.uk
Pras PathmanathanFood and Drug AdministrationDirección de correo verificada de fda.hhs.gov
Marina RiabizKing's College LondonDirección de correo verificada de kcl.ac.uk
Keith WordenUniversity of SheffieldDirección de correo verificada de sheffield.ac.uk
John WalmsleyStaff Scientist, BridgeSource Medical Corp.Dirección de correo verificada de bridgesourcemedical.com
Yasser AboelkassemAssistant Professor - University of MichiganDirección de correo verificada de umich.edu

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Dominic G Whittaker

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Quantitative Systems Pharmacology Drug Development Systems Biology


Título Ordenar por citas Ordenar por año Ordenar por título	Citado por Citado por	Año
Calibration of ionic and cellular cardiac electrophysiology models DG Whittaker, M Clerx, CL Lei, DJ Christini, GR Mirams Wiley Interdisciplinary Reviews: Systems Biology and Medicine 12 (4), e1482, 2020	111	2020
Considering discrepancy when calibrating a mechanistic electrophysiology model CL Lei, S Ghosh, DG Whittaker, Y Aboelkassem, KA Beattie, CD Cantwell, ... Philosophical Transactions of the Royal Society A 378 (2173), 20190349, 2020	63	2020
Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage-clamp experiments CL Lei, M Clerx, DG Whittaker, DJ Gavaghan, TP de Boer, GR Mirams Philosophical Transactions of the Royal Society A 378 (2173), 20190348, 2020	61	2020
Emerging therapeutic targets in the short QT syndrome JC Hancox, DG Whittaker, C Du, AG Stuart, H Zhang Expert opinion on therapeutic targets 22 (5), 439-451, 2018	56	2018
Synergistic anti-arrhythmic effects in human atria with combined use of sodium blockers and acacetin H Ni, DG Whittaker, W Wang, WR Giles, SM Narayan, H Zhang Frontiers in Physiology 8, 946, 2017	41	2017
Computational analysis of the mode of action of disopyramide and quinidine on hERG-linked short QT syndrome in human ventricles DG Whittaker, H Ni, AP Benson, JC Hancox, H Zhang Frontiers in physiology 8, 759, 2017	39	2017
Atrial arrhythmogenicity of KCNJ2 mutations in short QT syndrome: Insights from virtual human atria DG Whittaker, H Ni, A El Harchi, JC Hancox, H Zhang PLoS Computational Biology 13 (6), e1005593, 2017	33	2017
Human Atrial Arrhythmogenesis and Sinus Bradycardia in KCNQ1-Linked Short QT Syndrome: Insights From Computational Modelling DG Whittaker, MA Colman, H Ni, JC Hancox, H Zhang Frontiers in physiology 9, 1402, 2018	32	2018
In silico investigation of a KCNQ1 mutation associated with short QT syndrome I Adeniran, DG Whittaker, A El Harchi, JC Hancox, H Zhang Scientific reports 7 (1), 8469, 2017	28	2017
Multi-scale approaches for the simulation of cardiac electrophysiology: II–Tissue-level structure and function AP Benson, HJ Stevenson-Cocks, DG Whittaker, E White, MA Colman Methods 185, 60-81, 2021	20	2021
Electrophysiological characterization of the hERG R56Q LQTS variant and targeted rescue by the activator RPR260243 JM Kemp, DG Whittaker, R Venkateshappa, ZK Pang, R Johal, V Sergeev, ... Journal of General Physiology 153 (10), e202112923, 2021	16	2021
In silico Assessment of Pharmacotherapy for Human Atrial Patho-Electrophysiology Associated With hERG-Linked Short QT Syndrome DG Whittaker, JC Hancox, H Zhang Frontiers in physiology 9, 1888, 2019	16	2019
A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer CL Lei, A Fabbri, DG Whittaker, M Clerx, MJ Windley, AP Hill, GR Mirams, ... Wellcome Open Research 5, 152, 2021	15	2021
Empirical quantification of predictive uncertainty due to model discrepancy by training with an ensemble of experimental designs: an application to ion channel kinetics JG Shuttleworth, CL Lei, DG Whittaker, MJ Windley, AP Hill, SP Preston, ... Bulletin of Mathematical Biology 86 (1), 2, 2024	14	2024
Cardiac TdP risk stratification modelling of anti-infective compounds including chloroquine and hydroxychloroquine DG Whittaker, RA Capel, M Hendrix, XHS Chan, N Herring, NJ White, ... Royal Society open science 8 (4), 210235, 2021	13	2021
Multi-scale approaches for the simulation of cardiac electrophysiology: I–Sub-cellular and stochastic calcium dynamics from cell to organ MA Colman, M Holmes, DG Whittaker, I Jayasinghe, AP Benson Methods 185, 49-59, 2021	13	2021
A parameter representing missing charge should be considered when calibrating action potential models YSHM Barral, JG Shuttleworth, M Clerx, DG Whittaker, K Wang, ... Frontiers in Physiology 13, 879035, 2022	10	2022
Investigation of the role of myocyte orientations in cardiac arrhythmia using image-based models DG Whittaker, AP Benson, I Teh, JE Schneider, MA Colman Biophysical Journal 117 (12), 2396-2408, 2019	10	2019
Learning from studying very rare cardiac conditions: the example of short QT syndrome JC Hancox, DG Whittaker, H Zhang, AG Stuart Journal of Congenital Cardiology 3, 1-15, 2019	9	2019
The short QT syndrome JC Hancox, MJ McPate, A El Harchi, AS Butler, Y Zhang, DG Whittaker, ... Heart Rate and Rhythm: Molecular Basis, Pharmacological Modulation and …, 2023	8	2023

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