| Escherichia coli cell surface perturbation and disruption induced by antimicrobial peptides BP100 and pepR CS Alves, MN Melo, HG Franquelim, R Ferre, M Planas, L Feliu, E Bardají, ... Journal of Biological Chemistry 285 (36), 27536-27544, 2010 | 272 | 2010 |
| HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants MD Altman, A Ali, GSK Kumar Reddy, MNL Nalam, SG Anjum, H Cao, ... Journal of the American Chemical Society 130 (19), 6099-6113, 2008 | 144 | 2008 |
| Brownian dynamics simulation of rigid particles of arbitrary shape in external fields MX Fernandes, JG de la Torre Biophysical journal 83 (6), 3039-3048, 2002 | 137 | 2002 |
| Dual inhibitors of P-glycoprotein and tumor cell growth:(re) discovering thioxanthones A Palmeira, MH Vasconcelos, A Paiva, MX Fernandes, M Pinto, E Sousa Biochemical pharmacology, 2012 | 133 | 2012 |
| Screening drug-like compounds by docking to homology models: a systematic study V Kairys, MX Fernandes, MK Gilson Journal of chemical information and modeling 46 (1), 365-379, 2006 | 108 | 2006 |
| Calculation of hydrodynamic properties of small nucleic acids from their atomic structure MX Fernandes, A Ortega, MC Lopez Martinez, J García De La Torre Nucleic acids research 30 (8), 1782-1788, 2002 | 102 | 2002 |
| New uses for old drugs: pharmacophore‐based screening for the discovery of P‐glycoprotein inhibitors A Palmeira, F Rodrigues, E Sousa, M Pinto, MH Vasconcelos, ... Chemical biology & drug design 78 (1), 57-72, 2011 | 79 | 2011 |
| Lipid membrane-induced optimization for ligand–receptor docking: recent tools and insights for the “membrane catalysis” model MARB Castanho, MX Fernandes European Biophysics Journal 35, 92-103, 2006 | 78 | 2006 |
| Design of mutation‐resistant HIV protease inhibitors with the substrate envelope hypothesis S Chellappan, GS Kiran Kumar Reddy, A Ali, MNL Nalam, SG Anjum, ... Chemical Biology & Drug Design 69 (5), 298-313, 2007 | 73 | 2007 |
| Discovery of a new small-molecule inhibitor of p53–MDM2 interaction using a yeast-based approach M Leao, C Pereira, A Bisio, Y Ciribilli, AM Paiva, N Machado, A Palmeira, ... Biochemical Pharmacology 85 (9), 1234-1245, 2013 | 70 | 2013 |
| Evaluation of the substrate envelope hypothesis for inhibitors of HIV‐1 protease S Chellappan, V Kairys, MX Fernandes, C Schiffer, MK Gilson Proteins: structure, function, and bioinformatics 68 (2), 561-567, 2007 | 68 | 2007 |
| An analytical solution to the problem of the orientation of rigid particles by planar obstacles. Application to membrane systems and to the calculation of dipolar couplings in … MX Fernandes, P Bernado, M Pons, J García de la Torre Journal of the American Chemical Society 123 (48), 12037-12047, 2001 | 68 | 2001 |
| Enantioseparation and chiral recognition mechanism of new chiral derivatives of xanthones on macrocyclic antibiotic stationary phases C Fernandes, ME Tiritan, Q Cass, V Kairys, MX Fernandes, M Pinto Journal of Chromatography A 1241, 60-68, 2012 | 60 | 2012 |
| Insights into the In Vitro Antitumor Mechanism of Action of a New Pyranoxanthone A Palmeira, A Paiva, E Sousa, H Seca, GM Almeida, RT Lima, ... Chemical biology & drug design 76 (1), 43-58, 2010 | 57 | 2010 |
| Structure and ligand-based design of P-glycoprotein inhibitors: a historical perspective A Palmeira, E Sousa, M Helena Vasconcelos, M Pinto, M X Fernandes Current pharmaceutical design 18 (27), 4197-4214, 2012 | 54 | 2012 |
| Joint determination by Brownian dynamics and fluorescence quenching of the in-depth location profile of biomolecules in membranes MX Fernandes, JG de la Torre, M Castanho Analytical biochemistry 307 (1), 1-12, 2002 | 51 | 2002 |
| Anti‐Proliferative 1, 4‐Dihydropyridine and Pyridine Derivatives Synthesized through a Catalyst‐Free, One‐Pot Multi‐Component Reaction MG Sharma, RM Vala, DM Patel, I Lagunes, MX Fernandes, JM Padrón, ... ChemistrySelect 3 (43), 12163-12168, 2018 | 47 | 2018 |
| Analysis of occurrence patterns and biological factors of cetaceans based on long‐term and fine‐scale data from platforms of opportunity: Madeira Island as a case study F Alves, R Ferreira, M Fernandes, Z Halicka, L Dias, A Dinis Marine Ecology 39 (2), e12499, 2018 | 46 | 2018 |
| Calculation of the solution properties of flexible macromolecules: methods and applications J Garcia de la Torre, HE Pérez Sánchez, A Ortega, JG Hernandez, ... European Biophysics Journal 32, 477-486, 2003 | 41 | 2003 |
| Inhibition of the mTOR pathway: A new mechanism of β cell toxicity induced by tacrolimus AE Rodriguez-Rodriguez, J Donate-Correa, J Rovira, G Cuesto, ... American Journal of Transplantation 19 (12), 3240-3249, 2019 | 39 | 2019 |
