| The consensus molecular subtypes of colorectal cancer J Guinney, R Dienstmann, X Wang, A De Reynies, A Schlicker, ... Nature medicine 21 (11), 1350-1356, 2015 | 5109 | 2015 |
| Prospective derivation of a living organoid biobank of colorectal cancer patients M Van de Wetering, HE Francies, JM Francis, G Bounova, F Iorio, A Pronk, ... Cell 161 (4), 933-945, 2015 | 2338 | 2015 |
| Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes AV Biankin, N Waddell, KS Kassahn, MC Gingras, LB Muthuswamy, ... Nature 491 (7424), 399-405, 2012 | 2300 | 2012 |
| Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions L Guelen, L Pagie, E Brasset, W Meuleman, MB Faza, W Talhout, ... Nature 453 (7197), 948-951, 2008 | 2216 | 2008 |
| A landscape of pharmacogenomic interactions in cancer F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ... Cell 166 (3), 740-754, 2016 | 1957 | 2016 |
| A living biobank of breast cancer organoids captures disease heterogeneity N Sachs, J De Ligt, O Kopper, E Gogola, G Bounova, F Weeber, ... Cell 172 (1), 373-386. e10, 2018 | 1771 | 2018 |
| Concordance among gene-expression–based predictors for breast cancer C Fan, DS Oh, L Wessels, B Weigelt, DSA Nuyten, AB Nobel, ... New England Journal of Medicine 355 (6), 560-569, 2006 | 1737 | 2006 |
| Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma I Varela, P Tarpey, K Raine, D Huang, CK Ong, P Stephens, H Davies, ... Nature 469 (7331), 539-542, 2011 | 1457 | 2011 |
| Large-scale genotyping identifies 41 new loci associated with breast cancer risk K Michailidou, P Hall, A Gonzalez-Neira, M Ghoussaini, J Dennis, ... Nature genetics 45 (4), 353-361, 2013 | 1311 | 2013 |
| Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation D Peric-Hupkes, W Meuleman, L Pagie, SWM Bruggeman, I Solovei, ... Molecular cell 38 (4), 603-613, 2010 | 1165 | 2010 |
| Reversible and adaptive resistance to BRAF (V600E) inhibition in melanoma C Sun, L Wang, S Huang, GJJE Heynen, A Prahallad, C Robert, ... Nature 508 (7494), 118-122, 2014 | 944 | 2014 |
| Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial L Voorwerk, M Slagter, HM Horlings, K Sikorska, KK van de Vijver, ... Nature medicine 25 (6), 920-928, 2019 | 828 | 2019 |
| Refinement of breast cancer classification by molecular characterization of histological special types B Weigelt, HM Horlings, B Kreike, MM Hayes, M Hauptmann, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2008 | 729 | 2008 |
| Identification of CMTM6 and CMTM4 as PD-L1 protein regulators R Mezzadra, C Sun, LT Jae, R Gomez-Eerland, E De Vries, W Wu, ... Nature 549 (7670), 106-110, 2017 | 645 | 2017 |
| Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients SN Ooft, F Weeber, KK Dijkstra, CM McLean, S Kaing, E van Werkhoven, ... Science translational medicine 11 (513), eaay2574, 2019 | 633 | 2019 |
| Converting a breast cancer microarray signature into a high-throughput diagnostic test AM Glas, A Floore, LJMJ Delahaye, AT Witteveen, RCF Pover, N Bakx, ... BMC genomics 7 (1), 278, 2006 | 591 | 2006 |
| Gene expression profiles of primary breast tumors maintained in distant metastases B Weigelt, AM Glas, LFA Wessels, AT Witteveen, JL Peterse, ... Proceedings of the National Academy of Sciences 100 (26), 15901, 2003 | 580 | 2003 |
| Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer X Liu, H Holstege, H Van Der Gulden, M Treur-Mulder, J Zevenhoven, ... Proceedings of the National Academy of Sciences 104 (29), 12111, 2007 | 546 | 2007 |
| An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas P Roepman, LFA Wessels, N Kettelarij, P Kemmeren, AJ Miles, ... Nature genetics 37 (2), 182-186, 2005 | 524 | 2005 |
| Constitutive nuclear lamina–genome interactions are highly conserved and associated with A/T-rich sequence W Meuleman, D Peric-Hupkes, J Kind, JB Beaudry, L Pagie, M Kellis, ... Genome research 23 (2), 270-280, 2013 | 511 | 2013 |
Jos JonkersProfessor at Leiden University and group leader at Netherlands Cancer Institute, Oncode InstituteBestätigte E-Mail-Adresse bei nki.nl
