Jeremy Ewan Turnbull
Jeremy Ewan Turnbull
Johnston Professor of Biochemistry
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Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor.
SH Kim, J Turnbull, S Guimond
The Journal of endocrinology 209 (2), 139-151, 2011
Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate.
JE Turnbull, DG Fernig, Y Ke, MC Wilkinson, JT Gallagher
Journal of Biological Chemistry 267 (15), 10337-10341, 1992
Heparan sulfate: decoding a dynamic multifunctional cell regulator
J Turnbull, A Powell, S Guimond
Trends in cell biology 11 (2), 75-82, 2001
Examination of the substrate specificity of heparin and heparan sulfate lyases
RJ Linhardt, JE Turnbull, HM Wang, D Loganathan, JT Gallagher
Biochemistry 29 (10), 2611-2617, 1990
Heparan sulfate oligosaccharides require 6-O-sulfation for promotion of basic fibroblast growth factor mitogenic activity
DA Pye, RR Vives, JE Turnbull, P Hyde, JT Gallagher
Journal of Biological Chemistry 273 (36), 22936-22942, 1998
Interactions of heparin/heparan sulfate with proteins: appraisal of structural factors and experimental approaches
AK Powell, EA Yates, DG Fernig, JE Turnbull
Glycobiology 14 (4), 17R-30R, 2004
Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the spike S1 receptor-binding domain with heparin
CJ Mycroft-West, D Su, I Pagani, TR Rudd, S Elli, NS Gandhi, ...
Thrombosis and haemostasis 120 (12), 1700-1715, 2020
Modular synthesis of heparan sulfate oligosaccharides for structure− activity relationship studies
S Arungundram, K Al-Mafraji, J Asong, FE Leach III, IJ Amster, A Venot, ...
Journal of the American Chemical Society 131 (47), 17394-17405, 2009
Specific heparan sulfate saccharides mediate the activity of basic fibroblast growth factor.
A Walker, JE Turnbull, JT Gallagher
Journal of Biological Chemistry 269 (2), 931-935, 1994
Cell surface syndecan-1 on distinct cell types differs in fine structure and ligand binding of its heparan sulfate chains.
M Kato, H Wang, M Bernfield, JT Gallagher, JE Turnbull
Journal of Biological Chemistry 269 (29), 18881-18890, 1994
Identification of the heparan sulfate binding sites in the cellular prion protein
RG Warner, C Hundt, S Weiss, JE Turnbull
Journal of Biological Chemistry 277 (21), 18421-18430, 2002
Structural modification of fibroblast growth factor-binding heparan sulfate at a determinative stage of neural development
YG Brickman, MD Ford, JT Gallagher, V Nurcombe, PF Bartlett, ...
Journal of Biological Chemistry 273 (8), 4350-4359, 1998
Fibroblast growth factor receptor signalling is dictated by specific heparan sulphate saccharides
SE Guimond, JE Turnbull
Current Biology 9 (22), 1343-1346, 1999
The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding
C Mycroft-West, D Su, S Elli, Y Li, S Guimond, G Miller, J Turnbull, E Yates, ...
BioRxiv, 2020.02. 29.971093, 2020
Fine structure of heparan sulfate regulates syndecan-1 function and cell behavior.
RD Sanderson, JE Turnbull, JT Gallagher, AD Lander
Journal of Biological Chemistry 269 (18), 13100-13106, 1994
Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's β-secretase
Z Scholefield, EA Yates, G Wayne, A Amour, W McDowell, JE Turnbull
The Journal of cell biology 163 (1), 97-107, 2003
A strategy for rapid sequencing of heparan sulfate and heparin saccharides
JE Turnbull, JJ Hopwood, JT Gallagher
Proceedings of the National Academy of Sciences 96 (6), 2698-2703, 1999
Emerging glycomics technologies
JE Turnbull, RA Field
Nature Chemical Biology 3 (2), 74-77, 2007
Distribution of iduronate 2-sulphate residues in heparan sulphate. Evidence for an ordered polymeric structure
JE Turnbull, JT Gallagher
Biochemical journal 273 (3), 553-559, 1991
Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2
DC West, CG Rees, L Duchesne, SJ Patey, CJ Terry, JE Turnbull, ...
Journal of Biological Chemistry 280 (14), 13457-13464, 2005
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