| Multi-scale approaches for the simulation of cardiac electrophysiology: I–Sub-cellular and stochastic calcium dynamics from cell to organ MA Colman, M Holmes, DG Whittaker, I Jayasinghe, AP Benson Methods 185, 49-59, 2021 | 13 | 2021 |
| Increased SERCA2a sub-cellular heterogeneity in right-ventricular heart failure inhibits excitation-contraction coupling and modulates arrhythmogenic dynamics M Holmes, ME Hurley, TMD Sheard, AP Benson, I Jayasinghe, ... Philosophical Transactions of the Royal Society B 377 (1864), 20210317, 2022 | 9 | 2022 |
| Harnessing 12-lead ECG and MRI data to personalise repolarisation profiles in cardiac digital twin models for enhanced virtual drug testing J Camps, ZJ Wang, R Doste, LA Berg, M Holmes, B Lawson, J Tomek, ... Medical Image Analysis 100, 103361, 2025 | 5 | 2025 |
| Cardiac digital twin pipeline for virtual therapy evaluation J Camps, ZJ Wang, R Doste, M Holmes, B Lawson, J Tomek, K Burrage, ... arXiv preprint arXiv:2401.10029, 2024 | 3 | 2024 |
| Sub-cellular Heterogeneity in SERCA Determines Spatial Calcium Dynamics in Cardiomyocytes M Holmes, ME Hurley, TMD Sheard, HJ Stevenson-Cocks, A Benson, ... Biophysical Journal 118 (3), 172a-173a, 2020 | 1 | 2020 |
| Investigating calcium-mediated arrhythmias via a computational model of a rabbit atrial myocyte M Holmes, AP Benson, OV Aslanidi, MA Colman 2018 Computing in Cardiology Conference (CinC) 45, 1-4, 2018 | 1 | 2018 |
| An Automated Computational Pipeline for Generating Large-Scale Cohorts of Patient-Specific Ventricular Models in Electromechanical In Silico Trials R Doste, J Camps, ZJ Wang, LA Berg, M Holmes, H Smith, M Beetz, L Li, ... arXiv preprint arXiv:2503.03706, 2025 | | 2025 |
| Calibration and validation strategy for electromechanical cardiac digital twins ZJ Wang, M Holmes, R Doste, J Camps, F Margara, M Vazquez, ... bioRxiv, 2025.03. 06.638897, 2025 | | 2025 |
| In silico model predicts drug-induced changes on cardiac cellular contractility in simulated populations of human ventricular cardiomyocytes C Trovato, S Longobardi, E Passini, K Beattie, M Holmes, K Chaudhary, ... | | 2024 |
| Open Source Cardiac Digital Twinning of Human Ventricular Repolarisation from 12-Lead ECG and MRI J Camps, ZJ Wang, R Doste, LA Berg, M Holmes, B Lawson, J Tomek, ... Artificial Intelligence Research and Development, 126-135, 2024 | | 2024 |
| The Influence of Calcium Handling Variability on Cardiac Electrophysiology in Ventricular and Atrial Myocytes M Holmes University of Leeds, 2021 | | 2021 |
| In silico predictions of drug-induced changes in human cardiac contractility agree with experimental recordings C Trovato, S Longobardi, E Passini, KA Beattie, M Holmes, K Chaudhary, ... Frontiers in Pharmacology 16, 1500668, 0 | | |
| Sensitivity of ECG and ejection fraction to human electromechanical myocardial properties in post-myocardial infarction ZJ Wang, M Holmes, R Doste, J Camps, X Zhou, B Rodriguez | | |
| Online Supplement: Increased SERCA2a sub-cellular heterogeneity in right-ventricular heart failure inhibits excitation-contraction coupling and modulates arrhythmogenic dynamics M Holmes, ME Hurley, TMD Sheard, AP Benson, I Jayasinghe, ... | | |
| A Novel Model of the Rabbit Atrial Myocyte for the Study of Ca2+ Mediated Arrhythmia M Holmes, AP Benson, OV Aslanidi, MA Colman | | |
